New manuscript on rapid protein evolution using protein language models
Today, we introduce EVOLVEpro, a few-shot active learning framework to rapidly improve protein activity using a combination of PLMs and...
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Abudayyeh-Gootenberg Lab
Building and applying the next generation of molecular tools
Research
"Progress in science depends on new techniques, new discoveries and new ideas, probably in that order."
– Sydney Brenner
The AbuGoot lab combines natural biological discovery and molecular engineering to develop a suite of new tools for manipulation of DNA, RNA, and cellular states – the cellular engineering toolbox. These tools have the ability to push our understanding of complex systems, provide novel diagnostic insights, and enable new platforms of therapeutics. We are enthusiastic about applying these tools to multiple areas, including cellular fate, aging, and genetic disease.
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Latest Publications
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