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Abudayyeh-Gootenberg Lab

Building and applying the next generation of molecular tools

Research

"Progress in science depends on new techniques, new discoveries and new ideas, probably in that order."
– Sydney Brenner

The AbuGoot lab combines natural biological discovery and molecular engineering to develop a suite of new tools for manipulation of DNA, RNA, and cellular states – the cellular engineering toolbox. These tools have the ability to push our understanding of complex systems, provide novel diagnostic insights, and enable new platforms of therapeutics. We are enthusiastic about applying these tools to multiple areas, including cellular fate, aging, and genetic disease.

News & Events

Latest Publications

Programmable biology through artificial intelligence: from nucleic acids to proteins to cells

Nature Methods

Aug 9, 2024

Rapid protein evolution by few-shot learning with a protein language model

bioRxiv

Jul 18, 2024

CRISPR technologies for genome, epigenome and transcriptome editing

Nat. Rev. Molecular Cell Biology

Feb 2, 2024

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